What challenges did the Homesteaders face as they tried to establish themselves in the West?

Homesteaders faced numerous challenges. The Great Plains' environment was harsh, with extreme weather conditions, from blizzards to droughts. Many settlers were inexperienced in farming and had to learn how to cultivate the arid land. There were also challenges related to building homes, often from sod or other available materials. Additionally, homesteaders sometimes faced conflicts with Native American tribes and had to protect their claims from cattle ranchers and others who might dispute their land rights.